HitPredict

Interactor 1: ASXL1 (Q8IXJ9)
Polycomb group protein ASXL1 (Additional sex combs-like protein 1)
Gene: ASXL1

Interactor 2: MBD5 (Q9P267)
Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5)
Gene: MBD5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	36180891, 27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1541 Hs			1 1494
+	Hs
		1176274 ASXL2_HUMAN (1474-1541): 1.14e-23: 111: 55.88		MBD5_HUMAN (1-1494): 0: 2832: 100.00
+	Hs
		1319310 ASXL3_HUMAN (363-661): 2.63e-10: 67.9: 25.72		MBD5_HUMAN (1-1494): 0: 2832: 100.00
+	Hs
		1220800 ASXL1_HUMAN (1-1541): 0: 2382: 100.00		MBD6_HUMAN (1-133): 5.96e-47: 186: 55.97
+	Hs
		1176257 ASXL2_HUMAN (1474-1541): 1.14e-23: 111: 55.88		MBD6_HUMAN (1-133): 5.96e-47: 186: 55.97
+	Hs
		1288481 ASXL3_HUMAN (363-661): 2.63e-10: 67.9: 25.72		MBD6_HUMAN (1-133): 5.96e-47: 186: 55.97
+	Dm
		65926 ASX_DROME (1491-1539): 1.08e-10: 69.1: 51.02		MBD56_DROME (24-107): 1.65e-29: 130: 39.29