HitPredict

Interactor 1: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1101 Hs			1 1186
+	Hs
		331844 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		1221647 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		NSD1_HUMAN (12-358): 2.19e-51: 201: 15.98
+	Hs
		170417 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		1221598 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		1221713 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		NSD3_HUMAN (3-359): 2.43e-44: 177: 14.64
+	Hs
		1221839 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Hs
		1221813 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		1221762 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		BAZ1A_HUMAN (5-252): 1.74e-36: 152: 14.63
+	Hs
		1017322 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		600184 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		1221560 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		TAF1L_HUMAN (109-254): 1.82e-23: 110: 25.66
+	Hs
		170514 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		1357683 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Hs
		1345726 SMC4_HUMAN (2-1073): 2.02e-73: 268: 12.37		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Hs
		1199219 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		311646 SMC2_HUMAN (51-1055): 9.8e-55: 210: 11.41		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Sc
		976012 SMC6_YEAST (46-1057): 1.56e-51: 200: 13.80		GCN5_YEAST (120-252): 1.1e-33: 137: 23.88
+	Hs
		170277 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		725269 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09