HitPredict

Interactor 1: YAF2 (Q8IY57)
YY1-associated factor 2
Gene: YAF2

Interactor 2: KDM2B (Q8NHM5)
Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B)
Gene: KDM2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	24981860, 28514442, 27705803, 27684187, 33961781, 22325352
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003712 - transcription coregulator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 180 Hs			1 1336
+	Hs
		1233111 RYBP_HUMAN (1-179): 5.8e-49: 160: 49.78		KDM2B_HUMAN (1-1336): 0: 1220: 100.00
+	Mm
		1158238 YAF2_MOUSE (1-180): 3.8e-76: 227: 91.67		KDM2B_MOUSE (43-1336): 0: 1146: 94.45
+	Mm
		1158234 RYBP_MOUSE (1-179): 3.52e-49: 160: 49.78		KDM2B_MOUSE (43-1336): 0: 1146: 94.45
+	Dm
		1367226 Q9W215_DROME (1-133): 1.35e-51: 163: 51.13		JHD1_DROME (46-1233): 0: 600: 24.77