HitPredict

Interactor 1: AMOL1 (Q8IY63)
Angiomotin-like protein 1
Gene: AMOTL1

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	26186194, 38280479, 20972459
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0035329 - hippo signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 956 Hs			1 400
+	Hs
		808761 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1222267 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		125569 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1220065 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1222264 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		MAGI1_HUMAN (10-212): 9.04e-40: 153: 15.74
+	Hs
		808183 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		1222274 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Mm
		1257594 AMOT_MOUSE (87-890): 3.68e-57: 216: 48.40		WWTR1_MOUSE (1-400): 7.96e-120: 355: 91.00
+	Hs
		1222263 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		1326795 AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Mm
		809078 AMOT_MOUSE (87-890): 3.68e-57: 216: 48.40		YAP1_MOUSE (15-400): 5.62e-100: 307: 41.30
+	Hs
		809041 AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808669 AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1327936 AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		125805 AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		125503 AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1118983 AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1300698 AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12		MAGI1_HUMAN (10-212): 9.04e-40: 153: 15.74
+	Hs
		808328 AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		808151 AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00