HitPredict

Interactor 1: AMOL1 (Q8IY63)
Angiomotin-like protein 1
Gene: AMOTL1

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24255178
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0035329 - hippo signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 956 Hs			1 1088
+	Hs
		325799 AMOL1_HUMAN (1-956): 6.37e-156: 486: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1344980 AMOL2_HUMAN (92-914): 4.21e-45: 177: 40.12		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1119070 AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		149340 CTRO_HUMAN (238-841): 1.53e-21: 103: 12.00		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325760 AMOT_HUMAN (87-890): 1.03e-41: 168: 40.18		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325935 MYH2_HUMAN (144-766): 4.84e-20: 98.5: 10.29		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325608 MYH1_HUMAN (131-766): 7.02e-20: 98.1: 10.19		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325955 MYH4_HUMAN (266-953): 1.39e-19: 97.4: 8.38		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		725079 MYH9_HUMAN (226-951): 4.21e-24: 111: 9.29		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30
+	Hs
		681696 MYH9_HUMAN (226-951): 4.21e-24: 111: 9.29		AKT1_HUMAN (532-1043): 2.2e-141: 435: 22.16
+	Hs
		724784 MYH9_HUMAN (226-951): 4.21e-24: 111: 9.29		KPCE_HUMAN (554-1010): 1.06e-129: 413: 29.92
+	Hs
		568567 MYH9_HUMAN (226-951): 4.21e-24: 111: 9.29		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		610795 MYH2_HUMAN (144-766): 4.84e-20: 98.5: 10.29		KAPCB_HUMAN (638-1022): 1.92e-133: 410: 31.36
+	Hs
		522538 MYH1_HUMAN (131-766): 7.02e-20: 98.1: 10.19		KAPCB_HUMAN (638-1022): 1.92e-133: 410: 31.36
+	Hs
		610802 MYH4_HUMAN (266-953): 1.39e-19: 97.4: 8.38		KAPCB_HUMAN (638-1022): 1.92e-133: 410: 31.36
+	Hs
		116964 MYH1_HUMAN (131-766): 7.02e-20: 98.1: 10.19		SGK1_HUMAN (608-1042): 1.07e-131: 408: 28.51
+	Hs
		568568 MYH10_HUMAN (82-725): 1.38e-18: 93.9: 10.26		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		724810 MYH9_HUMAN (226-951): 4.21e-24: 111: 9.29		ROCK1_HUMAN (640-1008): 1.28e-70: 260: 38.77
+	Rn
		222472 MRCKA_RAT (287-776): 2.02e-18: 93.5: 8.68		MRCKA_RAT (656-1007): 1.21e-74: 273: 40.67
+	Rn
		222476 MRCKA_RAT (287-776): 2.02e-18: 93.5: 8.68		MRCKB_RAT (658-1007): 1.95e-70: 260: 40.34