Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4
Interactor 2: EME1 (Q96AY2)
Crossover junction endonuclease EME1 (EC 3.1.22.-) (MMS4 homolog) (hMMS4)
Gene: EME1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.55 | 0.721 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31495888, 32398829, 37071664, 37059091, 19596235, 19595721, 19596236 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, enzymatic study, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000712 - resolution of meiotic recombination intermediates GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0046872 - metal ion binding GO:0072429 - response to intra-S DNA damage checkpoint signaling |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
