Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4
Interactor 2: SLX1 (Q9BQ83)
Structure-specific endonuclease subunit SLX1 (EC 3.1.-.-) (GIY-YIG domain-containing protein 1)
Gene: SLX1A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19596235, 19595721, 19596236, 24012755, 31495888, 32398829, 37071664, 37059091, 23093618 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GIY-YIG~Slx4 |
| Common GO terms | GO:0000724 - double-strand break repair via homologous recombination GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0010792 - DNA double-strand break processing involved in repair via single-strand annealing GO:0033557 - Slx1-Slx4 complex and 5 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
