HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: TE2IP (Q9NYB0)
Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Dopamine receptor-interacting protein 5) (Repressor/activator protein 1 homolog) (RAP1 homolog) (hRap1)
Gene: TERF2IP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	34187905, 31495888, 37071664, 19596235, 22902628
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005654 - nucleoplasm GO:0032206 - positive regulation of telomere maintenance
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1834 Hs			1 399
+	Hs
		801429 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		TE2IP_HUMAN (1-399): 0: 664: 100.00
+	Hs
		1057006 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		TE2IP_HUMAN (1-399): 0: 664: 100.00
+	Hs
		1170092 SRCAP_HUMAN (1206-1787): 5.26e-09: 64: 11.45		TE2IP_HUMAN (1-399): 0: 664: 100.00
+	Hs
		1270809 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		TE2IP_HUMAN (1-399): 0: 664: 100.00