Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: RTEL1 (Q9NZ71)
Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like)
Gene: RTEL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.669

The method score is based on:

Property Details
Experiments 32398829, 31495888, 37071664
Identification Methods affinity chromatography technology, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0032206 - positive regulation of telomere maintenance
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1834
Hs

1 1219
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024