Interactor 1: E2F1 (Q61501)
Transcription factor E2F1 (E2F-1)
Gene: E2F1
Interactor 2: HTRA2 (Q9JIY5)
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI)
Gene: HTRA2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.55 | 0.554 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26238290 |
| Identification Methods | affinity chromatography technology, enzymatic study, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000785 - chromatin GO:0005634 - nucleus GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage GO:0030900 - forebrain development GO:0043065 - positive regulation of apoptotic process |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
