HitPredict

Interactor 1: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 18285517, 20347429
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, ERCC4~ERCC4, FANCM-MHF_bd~FANCM-MHF_bd, Helicase_C~Helicase_C
Common GO terms GO:0000400 - four-way junction DNA binding
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003724 - RNA helicase activity
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2048
Hs

1 2048
+ At
+ Hs
+ Ce
+ At
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024