Interactor 1: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Interactor 2: CENPS (Q8N2Z9)
Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain-containing protein 1) (FANCM-associated histone fold protein 1) (FANCM-interacting histone fold protein 1) (Fanconi anemia-associated polypeptide of 16 kDa)
Gene: CENPS

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.90 0.923

The method score is based on:

Property Details
Experiments 20347428, 26625197, 24699063, 22510687, 20347429, 24390579, 33961781, 23886707
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, molecular sieving, x ray scattering
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-S~FANCM-MHF_bd
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 4 others

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Homologous interactions 0

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Last updated: 15 Jul 2024