Interactor 1: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Interactor 2: FAP24 (Q9BTP7)
Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa)
Gene: FAAP24

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.934

The method score is based on:

Property Details
Experiments 24003026, 23932590, 24699063, 18285517, 20347428, 20347429, 20064461, 17289582, 28514442, 23999858, 33961781
Identification Methods x-ray crystallography, pull down, affinity chromatography technology, biochemical, two hybrid, transmission electron microscopy, molecular sieving, gal4 vp16 complementation, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC4~PND
Common GO terms GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0036297 - interstrand cross-link repair
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024