HitPredict

Interactor 1: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Interactor 2: FANCL (Q9NW38)
E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL)
Gene: FANCL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.55 0.718

The method score is based on:

Property Details
Experiments 22343915, 27398742, 20347429, 18174376, 17396147, 16116422, 18285517, 20347428, 17289582, 16720839
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0036297 - interstrand cross-link repair
GO:0043240 - Fanconi anaemia nuclear complex
Homologous interactions 0

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Last updated: 15 Jul 2024