HitPredict

Interactor 1: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	19270156, 22017875
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2048 Hs			1 542
+	Hs
		1223022 FANCM_HUMAN (1-2048): 0: 1666: 100.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1102073 ERC6L_HUMAN (1-1232): 1.73e-116: 404: 11.51		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1336307 CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		321921 RIGI_HUMAN (52-637): 3.28e-125: 421: 20.09		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		1254435 CHD6_HUMAN (42-1218): 5.58e-109: 391: 12.33		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		658714 SMCA1_HUMAN (4-1033): 8.64e-110: 379: 13.04		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		134246 DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1059779 CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		571638 DDX5_HUMAN (13-334): 4.25e-20: 98.9: 16.10		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		197011 CHD3_HUMAN (29-1087): 1.86e-103: 372: 13.16		PRP4_HUMAN (320-536): 4.83e-42: 159: 22.13
+	Hs
		197020 CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88		PRP4_HUMAN (320-536): 4.83e-42: 159: 22.13
+	Hs
		1016272 CHD3_HUMAN (29-1087): 1.86e-103: 372: 13.16		TBL3_HUMAN (237-531): 4.06e-24: 108: 24.46
+	Sc
		697383 CHD1_YEAST (31-1157): 3.76e-102: 364: 12.01		TAF5_YEAST (240-478): 1.44e-24: 110: 29.26
+	Hs
		1016277 CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88		TBL3_HUMAN (237-531): 4.06e-24: 108: 24.46
+	Hs
		1018714 CHD3_HUMAN (29-1087): 1.86e-103: 372: 13.16		NLE1_HUMAN (125-224): 6.61e-09: 60.3: 6.00
+	Hs
		903535 CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		903234 CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		134154 DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		571382 DDX5_HUMAN (13-334): 4.25e-20: 98.9: 16.10		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		133956 DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92