Interactor 1: SIRB1 (O00241)
Signal-regulatory protein beta-1 (SIRP-beta-1) (CD172 antigen-like family member B) (CD antigen CD172b)
Gene: SIRPB1

Interactor 2: CD47 (Q08722)
Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47)
Gene: CD47

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 17070842
Identification Methods enzyme linked immunosorbent assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains V-set~V-set_CD47
Common GO terms GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0050766 - positive regulation of phagocytosis
GO:0050870 - positive regulation of T cell activation
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 398
Hs

1 323
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024