HitPredict

Interactor 1: RN168 (Q8IYW5)
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168)
Gene: RNF168

Interactor 2: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	33529165
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0006974 - DNA damage response GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 571 Hs			1 201
+	Hs
		919783 RN168_HUMAN (1-571): 6.89e-90: 289: 100.00		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		849367 RN168_HUMAN (1-571): 6.89e-90: 289: 100.00		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		851840 RN168_HUMAN (1-571): 6.89e-90: 289: 100.00		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		895843 RN168_HUMAN (1-571): 6.89e-90: 289: 100.00		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		896490 RN168_HUMAN (1-571): 6.89e-90: 289: 100.00		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27
+	Hs
		851848 RN169_HUMAN (13-432): 1.06e-29: 126: 23.85		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		829039 TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05		UBE2A_HUMAN (54-198): 1.67e-70: 212: 35.86