Interactor 1: DOCK3 (Q8IZD9)
Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP)
Gene: DOCK3

Interactor 2: DOCK4 (Q8N1I0)
Dedicator of cytokinesis protein 4
Gene: DOCK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DHR-2_Lobe_A~DHR-2_Lobe_A, DHR-2_Lobe_A~DHR-2_Lobe_B, DHR-2_Lobe_B~DHR-2_Lobe_C, DHR-2_Lobe_C~DHR-2_Lobe_C, DOCK-C2~DOCK-C2, DOCK-C2~DOCK_N, DOCK_N~SH3_2, SH3_2~SH3_2
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 3 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 2030
Hs

1 1966
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
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+ Dm
+ Mm

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Last updated: 15 Jul 2024