HitPredict

Interactor 1: UNC5B (Q8IZJ1)
Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1)
Gene: UNC5B

Interactor 2: FLRT3 (Q9NZU0)
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3)
Gene: FLRT3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21673655
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	I-set~LRR_8, LRR_8~TSP_1
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 945 Hs			1 649
+	Mm
		1164192 UNC5B_MOUSE (1-945): 0: 944: 92.38		FLRT1_MOUSE (7-649): 2.19e-117: 367: 58.15
+	Mm
		1206871 UNC5B_MOUSE (1-945): 0: 944: 92.38		FLRT2_MOUSE (8-649): 6.25e-106: 336: 44.70
+	Mm
		139750 UNC5C_MOUSE (32-944): 0: 873: 64.95		FLRT1_MOUSE (7-649): 2.19e-117: 367: 58.15
+	Dr
		69121 A9JR35_DANRE (32-945): 0: 833: 67.50		B8A507_DANRE (1-649): 3.34e-127: 391: 73.23
+	Mm
		139751 UNC5C_MOUSE (32-944): 0: 873: 64.95		FLRT2_MOUSE (8-649): 6.25e-106: 336: 44.70
+	Mm
		1164193 UNC5A_MOUSE (1-945): 0: 821: 51.95		FLRT1_MOUSE (7-649): 2.19e-117: 367: 58.15
+	Mm
		1164191 UNC5D_MOUSE (48-944): 0: 795: 53.66		FLRT1_MOUSE (7-649): 2.19e-117: 367: 58.15
+	Mm
		1206872 UNC5A_MOUSE (1-945): 0: 821: 51.95		FLRT2_MOUSE (8-649): 6.25e-106: 336: 44.70
+	Dr
		47569 A9JR35_DANRE (32-945): 0: 833: 67.50		A0A8M9PLL4_DANRE (31-649): 6.47e-101: 324: 45.53
+	Dr
		69122 A9JR35_DANRE (32-945): 0: 833: 67.50		F1QF54_DANRE (30-649): 7e-97: 314: 45.20
+	Mm
		1206870 UNC5D_MOUSE (48-944): 0: 795: 53.66		FLRT2_MOUSE (8-649): 6.25e-106: 336: 44.70
+	Hs
		195862 UNC5D_HUMAN (48-944): 0: 785: 53.29		FLRT2_HUMAN (11-649): 1.52e-104: 333: 44.55
+	Dr
		47580 A0A8M9QLH5_DANRE (5-240): 3.59e-38: 157: 17.34		B8JKM0_DANRE (10-440): 5.04e-80: 264: 24.32
+	Dr
		82309 Q90Z70_DANRE (5-240): 2.75e-37: 154: 17.13		B8JKM0_DANRE (10-440): 5.04e-80: 264: 24.32
+	Hs
		1166667 LRIG3_HUMAN (11-263): 1.61e-38: 157: 19.23		LRC4C_HUMAN (26-556): 4.78e-74: 251: 22.34
+	Dm
		621592 Q9GPP7_DROME (2-292): 2.1e-32: 138: 16.83		SLIT_DROME (58-371): 5.97e-46: 177: 22.60
+	Mm
		292557 ROBO1_MOUSE (2-257): 1.03e-40: 165: 16.79		SLIT3_MOUSE (25-167): 3.21e-31: 132: 28.77
+	Hs
		434617 TSP1_HUMAN (171-467): 9.32e-56: 212: 23.05		PGS1_HUMAN (135-294): 8.15e-10: 63.2: 32.10
+	Hs
		1166661 LRIG1_HUMAN (11-537): 2.34e-42: 170: 12.78		LRIG3_HUMAN (41-357): 5.86e-19: 93.6: 25.46
+	Dr
		94546 F1QFK4_DANRE (10-277): 1.28e-34: 145: 17.86		F1Q7Y5_DANRE (7-224): 6.99e-20: 96.3: 19.47