HitPredict

Interactor 1: CDK20 (Q8IZL9)
Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)
Gene: CDK20

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 1121
+	Hs
		625337 CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		254043 CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10		WDR1_HUMAN (538-1119): 1.07e-31: 134: 9.41
+	Hs
		415113 CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		960342 CDK5_HUMAN (1-294): 2.23e-128: 370: 45.09		FBW1B_HUMAN (258-535): 1.92e-29: 126: 13.88
+	Dm
		186188 CDK2_DROME (1-290): 2.59e-128: 371: 41.72		GBLP_DROME (252-508): 8.1e-28: 117: 16.11
+	Hs
		625543 CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	At
		1106372 MPK4_ARATH (7-334): 3.11e-132: 383: 32.04		LST81_ARATH (137-308): 8.15e-13: 72.5: 22.16
+	Hs
		415016 CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		841208 CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62		TAF5_HUMAN (191-376): 1.08e-13: 77.9: 23.71
+	At
		189013 MPK6_ARATH (9-327): 1.23e-129: 377: 33.64		GBLPA_ARATH (88-239): 1.98e-11: 68.8: 9.43
+	At
		1106623 MPK6_ARATH (9-327): 1.23e-129: 377: 33.64		GPLPC_ARATH (37-239): 6.59e-11: 66.8: 10.43
+	At
		189012 MPK3_ARATH (9-327): 8.15e-129: 374: 33.54		GBLPA_ARATH (88-239): 1.98e-11: 68.8: 9.43
+	At
		1106243 MPK3_ARATH (9-327): 8.15e-129: 374: 33.54		GPLPC_ARATH (37-239): 6.59e-11: 66.8: 10.43
+	At
		1106574 MPK6_ARATH (9-327): 1.23e-129: 377: 33.64		GPLPB_ARATH (357-532): 5.44e-09: 61.1: 10.00
+	At
		1106202 MPK3_ARATH (9-327): 8.15e-129: 374: 33.54		GPLPB_ARATH (357-532): 5.44e-09: 61.1: 10.00