HitPredict

Interactor 1: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Interactor 2: P55G (Q92569)
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
Gene: PIK3R3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20598684
Identification Methods	array technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH2~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 461
+	Hs
		337502 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		ABL1_HUMAN (3-461): 1.02e-93: 308: 16.12
+	Mm
		337634 ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93		ABL1_MOUSE (3-461): 1.14e-94: 310: 16.32
+	Hs
		655418 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		P85A_HUMAN (48-455): 9.1e-92: 295: 79.17
+	Mm
		643107 ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93		P85A_MOUSE (60-455): 4.12e-90: 291: 80.81
+	Hs
		129316 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		P85B_HUMAN (56-453): 2.19e-87: 283: 74.12
+	Hs
		337572 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		ABL1_HUMAN (3-461): 1.02e-93: 308: 16.12
+	Hs
		789078 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		ABL2_HUMAN (324-459): 5.26e-21: 98.5: 25.36
+	Hs
		411788 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		LCK_HUMAN (309-458): 5.54e-21: 97.3: 25.95
+	Hs
		412258 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		FYN_HUMAN (326-459): 6.82e-20: 94.2: 26.06
+	Hs
		442853 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		HCK_HUMAN (310-458): 1.43e-19: 93.1: 26.75
+	Hs
		433413 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		YES_HUMAN (317-459): 6.84e-19: 91.2: 23.72
+	Hs
		523060 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		SRC_HUMAN (323-459): 8.26e-19: 90.8: 24.14
+	Hs
		789126 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		FRK_HUMAN (256-459): 1.27e-18: 90: 24.04
+	Hs
		454841 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		FGR_HUMAN (323-459): 2.54e-18: 89.2: 26.21
+	Mm
		70555 ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93		B2RQ57_MOUSE (324-459): 1.07e-19: 94.2: 23.91
+	Hs
		433885 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		LYN_HUMAN (298-458): 6.17e-18: 88.1: 24.85
+	Hs
		146686 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		SOCS7_HUMAN (36-171): 6.33e-16: 82.2: 27.74
+	Hs
		855808 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		VAV2_HUMAN (38-159): 4.46e-13: 73.7: 22.95
+	Hs
		548732 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		VAV_HUMAN (65-170): 4e-12: 70.6: 27.36
+	Hs
		789094 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		ABL2_HUMAN (324-459): 5.26e-21: 98.5: 25.36