HitPredict

Interactor 1: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Interactor 2: WASF3 (Q9UPY6)
Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3)
Gene: WASF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0030027 - lamellipodium GO:0031209 - SCAR complex GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 502
+	Mm
		1206472 ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93		WASF2_MOUSE (1-484): 9.89e-66: 222: 42.56
+	Hs
		1224624 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57
+	Hs
		1224667 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Rn
		1124757 ABI1_RAT (1-508): 8.32e-118: 356: 91.34		WASF1_RAT (1-500): 1.87e-56: 199: 43.04
+	Hs
		1348432 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		WASF3_HUMAN (1-502): 1.19e-73: 243: 100.00
+	Hs
		1267032 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57
+	Hs
		1348444 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Dm
		94647 Q9Y0S9_DROME (1-504): 2.01e-77: 252: 34.72		F2FB81_DROME (1-209): 1.43e-42: 162: 54.55
+	Hs
		1052366 SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Mm
		1206482 VINEX_MOUSE (220-504): 3.43e-17: 86.7: 13.40		WASF2_MOUSE (1-484): 9.89e-66: 222: 42.56
+	Hs
		1349289 ITSN2_HUMAN (44-508): 6.18e-18: 89.8: 11.98		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Hs
		1267036 ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48		WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57
+	Hs
		235559 VINEX_HUMAN (229-504): 5.02e-15: 79.8: 15.58		WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57
+	Hs
		1350207 ABI3_HUMAN (250-502): 1.37e-16: 83.3: 25.48		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Hs
		203224 MYO1E_HUMAN (305-503): 2.96e-27: 118: 22.67		SYNJ1_HUMAN (11-499): 4.06e-38: 151: 11.82
+	Dm
		94643 DBNL_DROME (264-503): 3.06e-16: 83.5: 17.65		F2FB81_DROME (1-209): 1.43e-42: 162: 54.55
+	Hs
		203191 VINEX_HUMAN (229-504): 5.02e-15: 79.8: 15.58		SYNJ1_HUMAN (11-499): 4.06e-38: 151: 11.82
+	Hs
		1021688 MYO1E_HUMAN (305-503): 2.96e-27: 118: 22.67		CBP_HUMAN (153-498): 1.18e-22: 104: 13.84
+	Hs
		587810 NCF2_HUMAN (211-501): 2.81e-27: 117: 12.29		CBP_HUMAN (153-498): 1.18e-22: 104: 13.84
+	Mm
		1351630 PCLO_MOUSE (91-454): 1.32e-28: 122: 15.39		PCLO_MOUSE (126-483): 1.31e-11: 69.7: 9.57