HitPredict

Interactor 1: ASPM (Q8IZT6)
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)
Gene: ASPM

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0030496 - midbody
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3477 Hs			1 669
+	Hs
		148330 SPTB1_HUMAN (929-2995): 1.76e-100: 365: 9.24		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Mm
		1186645 ACTN1_MOUSE (937-1797): 3.18e-80: 288: 11.56		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Hs
		149277 SPTN4_HUMAN (921-3063): 6.29e-96: 351: 9.48		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Dm
		404218 ACTN_DROME (936-1799): 6.36e-87: 309: 12.79		MYSA_DROME (329-654): 6.59e-14: 77.9: 14.65
+	Hs
		148339 ACTN1_HUMAN (937-1797): 2.79e-81: 292: 11.76		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		148722 ACTN3_HUMAN (937-1801): 3.54e-79: 285: 12.39		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Mm
		93578 PLEC_MOUSE (1247-2889): 5.58e-36: 154: 6.93		DESP_MOUSE (337-641): 2.9e-11: 69.3: 18.65
+	Hs
		1343920 MYO5A_HUMAN (1780-2618): 8.03e-28: 126: 10.43		MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02
+	Hs
		1068617 PLEC_HUMAN (1241-2615): 6.18e-30: 134: 10.29		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		502933 MYH3_HUMAN (1250-2555): 5.44e-29: 130: 8.87		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Hs
		528432 MYH8_HUMAN (1640-2857): 3.32e-27: 124: 7.77		MYH13_HUMAN (161-669): 3.57e-13: 75.4: 11.94
+	Hs
		1068536 PLEC_HUMAN (1241-2615): 6.18e-30: 134: 10.29		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		528435 MYH8_HUMAN (1640-2857): 3.32e-27: 124: 7.77		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Hs
		1268124 MYO5A_HUMAN (1780-2618): 8.03e-28: 126: 10.43		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		148841 PLEC_HUMAN (1241-2615): 6.18e-30: 134: 10.29		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		502901 MYH3_HUMAN (1250-2555): 5.44e-29: 130: 8.87		MYH6_HUMAN (140-554): 2.32e-09: 63.1: 9.14
+	Hs
		522657 MYH7_HUMAN (1826-3039): 4.14e-23: 111: 9.72		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Mm
		513804 DMD_MOUSE (1569-3473): 3.28e-23: 111: 6.59		FYCO1_MOUSE (329-654): 1.42e-09: 63.5: 23.92
+	Mm
		513821 DMD_MOUSE (1569-3473): 3.28e-23: 111: 6.59		PLEC_MOUSE (326-624): 8.84e-09: 61.2: 19.02
+	Hs
		522585 MYH7_HUMAN (1826-3039): 4.14e-23: 111: 9.72		MYH7_HUMAN (140-540): 9.01e-09: 61.2: 9.45