HitPredict

Interactor 1: OPTN (Q8K3K8)
Optineurin
Gene: OPTN

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 21862579, 20174559, 27086836
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0045087 - innate immune response
GO:1904417 - positive regulation of xenophagy
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 584
Mm

1 729
+ Hs
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+ Mm
+ Mm
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+ Mm
+ Hs
+ Bt
+ Hs
+ Mm
+ Bt
+ Hs
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+ Mm
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+ Rn
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024