HitPredict

Interactor 1: RPTOR (Q8K4Q0)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Interactor 2: MTOR (Q9JLN9)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)
Gene: MTOR

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 23966835, 18664580, 20801936, 21045808
Identification Methods anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~WD40
Common GO terms GO:0001932 - regulation of protein phosphorylation
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0006974 - DNA damage response
and 15 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1335
Mm

1 2549
+ Mm
+ Hs
+ Dm
+ At
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Sp
+ Sc
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024