Interactor 1: MEN1 (O00255)
Menin
Gene: MEN1

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 27705803, 15199122, 24981860, 23508102, 35850772, 14992727, 15960975
Identification Methods affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0035097 - histone methyltransferase complex
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 610
Hs

1 334
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024