HitPredict

Interactor 1: CKB21 (Q8LF80)
Cyclin-dependent kinase B2-1 (CDKB2;1) (EC 2.7.11.22) (EC 2.7.11.23)
Gene: CDKB2-1

Interactor 2: CKS2 (Q9SJJ5)
Cyclin-dependent kinases regulatory subunit 2
Gene: CKS2

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.794

Property	Details
Experiments	20407024, 20706207
Identification Methods	protein complementation assay, two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CKS~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 At			1 83
+	At
		1228093 CKB22_ARATH (11-313): 4.28e-142: 405: 88.78		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188156 CKB21_ARATH (1-313): 1.22e-145: 414: 100.00		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		625283 CDK2_HUMAN (11-310): 3.47e-148: 419: 53.82		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	At
		188157 CKB22_ARATH (11-313): 4.28e-142: 405: 88.78		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		625164 CDK2_HUMAN (11-310): 3.47e-148: 419: 53.82		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	At
		1103378 CKB12_ARATH (11-309): 1.34e-136: 390: 62.01		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		621728 CDKA1_ARATH (11-307): 2.44e-136: 389: 54.03		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		639376 CKB11_ARATH (11-309): 4.59e-132: 379: 65.36		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	Hs
		895413 CDK3_HUMAN (11-311): 4.03e-141: 402: 52.65		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	At
		188147 CKB12_ARATH (11-309): 1.34e-136: 390: 62.01		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		188136 CDKA1_ARATH (11-307): 2.44e-136: 389: 54.03		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		706796 CDK3_HUMAN (11-311): 4.03e-141: 402: 52.65		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	At
		1321299 CDKD1_ARATH (5-312): 6.75e-128: 372: 41.56		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188137 CKB11_ARATH (11-309): 4.59e-132: 379: 65.36		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		414843 CDK1_HUMAN (11-308): 1.59e-134: 385: 54.85		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		414778 CDK1_HUMAN (11-308): 1.59e-134: 385: 54.85		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Dm
		618415 CDK1_DROME (11-307): 1.52e-129: 372: 48.99		Q9VHN1_DROME (2-71): 2.92e-37: 121: 65.71
+	Sp
		383445 CDK1_SCHPO (11-308): 1.53e-129: 372: 50.50		CKS1_SCHPO (1-80): 1.02e-34: 115: 46.07
+	Dm
		618387 CDK1_DROME (11-307): 1.52e-129: 372: 48.99		CKS1_DROME (3-71): 4.92e-35: 115: 68.12
+	Hs
		706797 CDK5_HUMAN (11-310): 2.46e-129: 371: 47.02		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22