HitPredict

Interactor 1: CKB22 (Q8LG64)
Cyclin-dependent kinase B2-2 (CDKB2;2) (EC 2.7.11.22) (EC 2.7.11.23)
Gene: CDKB2-2

Interactor 2: CKS2 (Q9SJJ5)
Cyclin-dependent kinases regulatory subunit 2
Gene: CKS2

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20407024
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CKS~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0007346 - regulation of mitotic cell cycle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 315 At			1 83
+	At
		1227962 CKB21_ARATH (13-315): 5.93e-140: 399: 88.78		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188157 CKB22_ARATH (1-315): 8.51e-143: 406: 100.00		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		188156 CKB21_ARATH (13-315): 5.93e-140: 399: 88.78		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		1103378 CKB12_ARATH (13-315): 1.51e-132: 380: 64.42		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		621728 CDKA1_ARATH (13-309): 6.3e-133: 380: 54.70		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	Hs
		625283 CDK2_HUMAN (13-312): 7.54e-140: 398: 55.15		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		625164 CDK2_HUMAN (13-312): 7.54e-140: 398: 55.15		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	At
		639376 CKB11_ARATH (13-315): 2.08e-128: 370: 65.48		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188136 CDKA1_ARATH (13-309): 6.3e-133: 380: 54.70		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		188147 CKB12_ARATH (13-315): 1.51e-132: 380: 64.42		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		895413 CDK3_HUMAN (13-313): 1.53e-136: 390: 52.65		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		706796 CDK3_HUMAN (13-313): 1.53e-136: 390: 52.65		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	At
		188137 CKB11_ARATH (13-315): 2.08e-128: 370: 65.48		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		414843 CDK1_HUMAN (13-309): 6.68e-131: 375: 58.39		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Dm
		618415 CDK1_DROME (13-307): 6.27e-128: 368: 51.01		Q9VHN1_DROME (2-71): 2.92e-37: 121: 65.71
+	Hs
		414778 CDK1_HUMAN (13-309): 6.68e-131: 375: 58.39		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Dm
		618387 CDK1_DROME (13-307): 6.27e-128: 368: 51.01		CKS1_DROME (3-71): 4.92e-35: 115: 68.12
+	Hs
		895414 CDK5_HUMAN (13-312): 3.27e-127: 366: 50.00		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Sp
		383445 CDK1_SCHPO (13-310): 2.2e-127: 367: 51.49		CKS1_SCHPO (1-80): 1.02e-34: 115: 46.07
+	Hs
		706797 CDK5_HUMAN (13-312): 3.27e-127: 366: 50.00		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22