HitPredict

Interactor 1: CD27B (Q8LGU6)
Cell division cycle protein 27 homolog B (CDC27 homolog B) (Protein HOBBIT)
Gene: CDC27B

Interactor 2: FZR3 (Q8LPL5)
Protein FIZZY-RELATED 3 (Cell cycle switch protein CCS52B)
Gene: FZR3

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	1.00	0.770

Property	Details
Experiments	20706207, 17944809
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_16~WD40
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0016567 - protein ubiquitination GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 744 At			1 481
+	At
		1228163 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		FZR1_ARATH (4-481): 6.07e-101: 312: 59.50
+	Hs
		1023023 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64
+	At
		1228172 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		CDC21_ARATH (263-480): 2.16e-37: 144: 21.21
+	At
		1228170 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		CDC22_ARATH (263-480): 2.59e-37: 143: 21.21
+	Hs
		1117531 Q4KMX6_HUMAN (282-743): 3.63e-70: 242: 15.04		FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64
+	At
		1225839 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		FZR2_ARATH (263-480): 1.23e-33: 134: 20.18
+	At
		1117915 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		CDC24_ARATH (263-479): 1e-33: 133: 20.78
+	Hs
		1160993 CTR9_HUMAN (47-743): 7.88e-57: 212: 12.09		FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64
+	At
		1108082 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		CD205_ARATH (304-481): 1.03e-21: 99.3: 19.37
+	Mm
		1246853 CDC16_MOUSE (433-718): 1.39e-76: 260: 20.47		FBXW7_MOUSE (96-409): 1.8e-61: 214: 15.48
+	Sc
		743217 CDC27_YEAST (5-738): 5.8e-84: 284: 23.69		AMA1_YEAST (131-458): 3.33e-38: 148: 30.61
+	Xl
		1150243 Q6DFI7_XENLA (433-718): 4.52e-81: 272: 21.81		Q8AVG7_XENLA (263-478): 1.05e-35: 140: 18.06
+	Sc
		743220 CDC27_YEAST (5-738): 5.8e-84: 284: 23.69		CDH1_YEAST (10-478): 1.33e-29: 123: 16.41
+	Hs
		1017371 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		CDC20_HUMAN (263-480): 3.22e-37: 144: 19.21
+	Mm
		1337483 APC7_MOUSE (282-743): 1.05e-69: 240: 15.04		CDC20_MOUSE (263-480): 9.46e-39: 148: 18.42
+	Sc
		640838 CDC27_YEAST (5-738): 5.8e-84: 284: 23.69		CDC20_YEAST (279-471): 1.9e-17: 87.3: 19.19
+	Mm
		1246856 CDC16_MOUSE (433-718): 1.39e-76: 260: 20.47		FZR1_MOUSE (94-293): 2.47e-17: 86.2: 13.53
+	Dm
		1337225 Q9I7L8_DROME (415-742): 8.87e-62: 221: 23.58		Q9W4H9_DROME (304-480): 2.7e-25: 110: 19.13
+	Mm
		1351677 APC7_MOUSE (282-743): 1.05e-69: 240: 15.04		FZR1_MOUSE (94-293): 2.47e-17: 86.2: 13.53
+	Dm
		1363029 Q9VCN6_DROME (349-718): 1.94e-48: 184: 16.71		Q9W4H9_DROME (304-480): 2.7e-25: 110: 19.13