HitPredict

Interactor 1: CD27B (Q8LGU6)
Cell division cycle protein 27 homolog B (CDC27 homolog B) (Protein HOBBIT)
Gene: CDC27B

Interactor 2: APC7 (Q8VY89)
Anaphase-promoting complex subunit 7 (Cyclosome subunit 7)
Gene: APC7

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	20706207
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_16~TPR_19, TPR_19~TPR_19
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0016567 - protein ubiquitination GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 744 At			1 558
+	At
		1228160 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		CD27B_ARATH (210-538): 6.26e-67: 232: 18.98
+	Hs
		1022909 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		Q4KMX6_HUMAN (1-557): 2.24e-71: 240: 26.82
+	Hs
		1023016 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		APC7_HUMAN (1-557): 2.92e-71: 240: 26.82
+	At
		71743 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		CDC16_ARATH (21-295): 6.14e-14: 76.4: 10.64
+	At
		1228171 CD27B_ARATH (1-744): 2.51e-130: 406: 100.00		CDC23_ARATH (283-549): 5.01e-12: 70.6: 12.96
+	Sc
		561118 CDC27_YEAST (5-738): 5.8e-84: 284: 23.69		CDC23_YEAST (13-402): 3.93e-23: 105: 10.40
+	Sc
		454909 CDC27_YEAST (5-738): 5.8e-84: 284: 23.69		CDC16_YEAST (222-545): 5.11e-21: 99.5: 15.27
+	Xl
		1150241 Q6DFI7_XENLA (433-718): 4.52e-81: 272: 21.81		Q6GQ04_XENLA (16-282): 3.37e-23: 106: 11.59
+	Hs
		672822 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		CDC27_HUMAN (1-244): 5.19e-25: 111: 10.36
+	Hs
		1023015 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		CDC23_HUMAN (179-549): 4.08e-23: 105: 14.21
+	Sc
		743211 CDC27_YEAST (5-738): 5.8e-84: 284: 23.69		CDC27_YEAST (224-462): 2.47e-12: 71.8: 18.60
+	Mm
		56872 APC7_MOUSE (282-743): 1.05e-69: 240: 15.04		CDC27_MOUSE (16-244): 5.01e-25: 111: 10.92
+	Xl
		1150214 Q6DDX5_XENLA (282-743): 1.13e-69: 240: 15.68		Q6GQ04_XENLA (16-282): 3.37e-23: 106: 11.59
+	Dm
		1363028 Q9VCN6_DROME (349-718): 1.94e-48: 184: 16.71		Q9VS37_DROME (73-415): 1.2e-31: 132: 12.47
+	Hs
		672848 Q5T8C6_HUMAN (433-718): 7.39e-47: 175: 18.06		CDC27_HUMAN (1-244): 5.19e-25: 111: 10.36
+	Hs
		1022949 TTC8_HUMAN (278-733): 1.13e-60: 215: 14.22		CDC16_HUMAN (37-326): 4.67e-10: 64.4: 9.77
+	Sc
		454891 CDC16_YEAST (425-732): 2.1e-39: 158: 19.38		CDC23_YEAST (13-402): 3.93e-23: 105: 10.40
+	Sc
		454883 CDC16_YEAST (425-732): 2.1e-39: 158: 19.38		CDC16_YEAST (222-545): 5.11e-21: 99.5: 15.27