HitPredict

Interactor 1: SPART (Q8N0X7)
Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1)
Gene: SPART

Interactor 2: SMUF1 (Q9HCE7)
E3 ubiquitin-protein ligase SMURF1 (hSMURF1) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF1) (SMAD ubiquitination regulatory factor 1) (SMAD-specific E3 ubiquitin-protein ligase 1)
Gene: SMURF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.717

The method score is based on:

Property Details
Experiments 20804422, 34662580, 28514442, 33961781, 19307600
Identification Methods enzymatic study, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030509 - BMP signaling pathway
GO:0030514 - negative regulation of BMP signaling pathway
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 666
Hs

1 757
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024