HitPredict

Interactor 1: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 25940091, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1335 Hs			1 543
+	Hs
		826760 RPTOR_HUMAN (1-1335): 0: 1440: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821307 RPTOR_HUMAN (1-1335): 0: 1440: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573361 RPTOR_HUMAN (1-1335): 0: 1440: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	At
		1275324 RTOR1_ARATH (27-1328): 0: 1169: 40.82		TCPH_ARATH (1-529): 0: 583: 67.67
+	Hs
		843281 RPTOR_HUMAN (1-1335): 0: 1440: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	At
		138357 RTOR1_ARATH (27-1328): 0: 1169: 40.82		TCPE_ARATH (3-524): 0: 551: 30.70
+	At
		660210 RTOR1_ARATH (27-1328): 0: 1169: 40.82		TCPA_ARATH (14-521): 1.16e-93: 298: 36.67
+	At
		1275293 RTOR1_ARATH (27-1328): 0: 1169: 40.82		TCPB_ARATH (8-528): 1.59e-88: 284: 35.36
+	Hs
		903467 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1306645 TBL1Y_HUMAN (1059-1334): 2.8e-54: 200: 13.54		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826807 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826601 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573406 FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821152 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		826848 TBL1Y_HUMAN (1059-1334): 2.8e-54: 200: 13.54		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573201 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821387 TBL1Y_HUMAN (1059-1334): 2.8e-54: 200: 13.54		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573446 TBL1Y_HUMAN (1059-1334): 2.8e-54: 200: 13.54		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843139 WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843357 TBL1Y_HUMAN (1059-1334): 2.8e-54: 200: 13.54		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79