HitPredict

Interactor 1: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Interactor 2: RRAGC (Q9HB90)
Ras-related GTP-binding protein C (Rag C) (RagC) (EC 3.6.5.-) (GTPase-interacting protein 2) (TIB929)
Gene: RRAGC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

The method score is based on:

Property	Details
Experiments	21981924, 18497260, 24337580, 31601708, 31601764, 21816923, 25567906, 25561175
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0005829 - cytosol and 5 others more... GO:0009267 - cellular response to starvation GO:0010507 - negative regulation of autophagy GO:0031669 - cellular response to nutrient levels GO:0071230 - cellular response to amino acid stimulus GO:0140767 - enzyme-substrate adaptor activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	1335
Hs

1	399

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024