HitPredict

Interactor 1: VPS52 (Q8N1B4)
Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein)
Gene: VPS52

Interactor 2: RNF41 (Q9H4P4)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.757

Property	Details
Experiments	25416956, 28542518, 27803151, 28973533, 29560723, 32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, pull down, protein complementation assay, fluorescent resonance energy transfer, proximity labelling technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 723 Hs			1 317
+	Hs
		1230741 VPS52_HUMAN (12-723): 0: 810: 100.00		TRIM1_HUMAN (2-299): 7.77e-40: 150: 16.57
+	Hs
		1230711 VPS52_HUMAN (12-723): 0: 810: 100.00		TRAF4_HUMAN (2-132): 2.42e-31: 124: 30.30
+	Hs
		1230749 VPS52_HUMAN (12-723): 0: 810: 100.00		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		1230681 VPS52_HUMAN (12-723): 0: 810: 100.00		LNX1_HUMAN (8-121): 1.33e-26: 111: 27.27
+	Mm
		1246880 EXOC1_MOUSE (36-699): 0: 594: 14.05		LNX2_MOUSE (8-123): 1.23e-30: 123: 29.06