HitPredict

Interactor 1: FXL14 (Q8N1E6)
F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14)
Gene: FBXL14

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 365
+	Hs
		73158 FXL14_HUMAN (1-418): 3.24e-73: 236: 100.00		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		1050095 SCRIB_HUMAN (132-417): 5.28e-30: 125: 12.95		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1354643 FXL17_HUMAN (178-414): 1.46e-22: 102: 18.11		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1356350 FBXL4_HUMAN (180-391): 3.38e-20: 94.7: 25.89		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1356393 FBXL2_HUMAN (255-416): 1.88e-20: 94.6: 25.90		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1222181 AMN1_HUMAN (230-380): 8.89e-10: 60.8: 26.23		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73189 FBXL7_HUMAN (201-417): 8.79e-29: 119: 24.35		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		72079 B3KM70_HUMAN (255-416): 3.88e-20: 93.8: 25.90		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73148 FXL19_HUMAN (176-406): 9.21e-17: 84.3: 20.87		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		174879 SCRIB_HUMAN (132-417): 5.28e-30: 125: 12.95		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		297112 FBXL4_HUMAN (180-391): 3.38e-20: 94.7: 25.89		TOM70_HUMAN (3-221): 1.5e-09: 61.4: 9.29