HitPredict

Interactor 1: S11IP (Q8N1F8)
Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1)
Gene: STK11IP

Interactor 2: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21903422
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1088 Hs			1 1032
+	Hs
		120165 S11IP_HUMAN (1-1088): 0: 1106: 100.00		TLR4_HUMAN (412-808): 6.07e-14: 78.3: 16.96
+	Hs
		237505 S11IP_HUMAN (1-1088): 0: 1106: 100.00		TLR2_HUMAN (15-575): 1.29e-12: 74: 16.93
+	Hs
		1073327 S11IP_HUMAN (1-1088): 0: 1106: 100.00		TLR1_HUMAN (433-605): 5.38e-10: 65.6: 20.81
+	At
		99021 RGI4_ARATH (1-465): 3.18e-59: 223: 15.31		FLS2_ARATH (2-612): 1.9e-74: 269: 19.28
+	At
		84500 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		BAME2_ARATH (2-566): 1.71e-64: 238: 18.85
+	At
		84489 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		BRL3_ARATH (14-645): 4.57e-56: 213: 17.20
+	At
		1325025 PXL1_ARATH (6-466): 4.71e-59: 223: 15.58		BRL3_ARATH (14-645): 4.57e-56: 213: 17.20
+	At
		84509 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		BRL2_ARATH (302-903): 2.58e-54: 208: 16.20
+	At
		84466 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		ERECT_ARATH (427-854): 8.79e-52: 199: 19.40
+	At
		1114706 PXL1_ARATH (6-466): 4.71e-59: 223: 15.58		ERECT_ARATH (427-854): 8.79e-52: 199: 19.40
+	At
		84498 MIK1_ARATH (2-475): 7.88e-57: 216: 17.19		GSO1_ARATH (448-874): 9.66e-50: 194: 18.75
+	At
		84507 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		Q9XGZ2_ARATH (1-373): 5.12e-46: 181: 17.04
+	At
		84511 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		BRL1_ARATH (2-513): 1.02e-43: 175: 16.19
+	At
		99012 RGI4_ARATH (1-465): 3.18e-59: 223: 15.31		ERL2_ARATH (2-266): 2.48e-29: 128: 17.08
+	At
		1167636 MIK1_ARATH (2-475): 7.88e-57: 216: 17.19		ERL2_ARATH (2-266): 2.48e-29: 128: 17.08
+	At
		84459 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		BAME1_ARATH (2-210): 7.17e-26: 117: 16.74
+	At
		99004 RGI4_ARATH (1-465): 3.18e-59: 223: 15.31		BAME1_ARATH (2-210): 7.17e-26: 117: 16.74
+	At
		84451 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		Y4361_ARATH (603-855): 5.28e-20: 98.4: 18.29
+	At
		84487 GSO1_ARATH (1-452): 2.19e-59: 225: 15.98		PEPR2_ARATH (2-203): 4.96e-16: 85.6: 17.87
+	At
		99002 RGI4_ARATH (1-465): 3.18e-59: 223: 15.31		RGI4_ARATH (2-151): 5.09e-16: 85.3: 18.67