HitPredict

Interactor 1: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 520 Hs			1 530
+	Hs
		369912 K2C1B_HUMAN (66-435): 6.29e-126: 381: 56.49		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		213976 KRT86_HUMAN (1-499): 1.62e-103: 321: 39.88		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368816 K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		318855 K2C75_HUMAN (2-516): 7.92e-95: 300: 48.22		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368794 K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		943688 KRT85_HUMAN (3-489): 6.87e-95: 299: 40.77		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1062061 K2C72_HUMAN (1-502): 4.44e-85: 274: 47.85		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		580147 K2C4_HUMAN (6-443): 3.19e-73: 243: 55.10		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369795 K2C79_HUMAN (9-442): 1.75e-88: 283: 53.14		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		611385 K22E_HUMAN (83-427): 1.05e-121: 372: 55.65		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		280820 KRT36_HUMAN (14-424): 2e-68: 228: 23.84		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369983 K2C78_HUMAN (1-520): 1.25e-79: 259: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368958 K2C4_HUMAN (6-443): 3.19e-73: 243: 55.10		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370133 KRT35_HUMAN (3-424): 1.7e-69: 231: 24.17		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		408982 K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487082 K2C3_HUMAN (83-428): 5.14e-68: 232: 62.07		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59