HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: WIZ (O95785)
Protein Wiz (Widely-interspaced zinc finger-containing protein) (Zinc finger protein 803)
Gene: WIZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 560 Hs			1 1651
+	Hs
		321860 CDY2_HUMAN (6-288): 5.39e-56: 198: 16.78		WIZ_HUMAN (1-1638): 0: 1453: 100.00
+	Hs
		321854 CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35		WIZ_HUMAN (1-1638): 0: 1453: 100.00
+	Hs
		321765 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		WIZ_HUMAN (1-1638): 0: 1453: 100.00
+	Hs
		1294636 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		ZN845_HUMAN (478-1285): 6.88e-136: 448: 11.20
+	Hs
		67424 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN850_HUMAN (480-1419): 1.32e-137: 456: 13.42
+	Hs
		316190 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN624_HUMAN (624-1277): 8.69e-120: 401: 12.81
+	Hs
		64140 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN729_HUMAN (464-1285): 1.44e-133: 449: 11.92
+	Hs
		123275 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		ZN546_HUMAN (199-297): 7.04e-18: 92.2: 14.56
+	Hs
		983755 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZNF91_HUMAN (569-1285): 1.72e-106: 371: 13.03
+	Hs
		316196 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN107_HUMAN (720-1285): 1.07e-64: 238: 11.26
+	Hs
		316155 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN644_HUMAN (696-815): 5.16e-44: 178: 40.95
+	Hs
		1331911 CDY2_HUMAN (6-288): 5.39e-56: 198: 16.78		ZN644_HUMAN (696-815): 5.16e-44: 178: 40.95
+	Hs
		1331903 CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35		ZN644_HUMAN (696-815): 5.16e-44: 178: 40.95
+	Hs
		316191 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZNF70_HUMAN (334-489): 1.97e-30: 128: 11.32
+	Hs
		316017 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZNF92_HUMAN (348-487): 2.13e-29: 127: 16.90
+	Hs
		316135 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN184_HUMAN (905-1285): 3.11e-22: 106: 11.86
+	Hs
		728565 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZNF93_HUMAN (557-1068): 3.57e-33: 139: 14.47
+	Hs
		1027027 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN568_HUMAN (323-489): 1.11e-28: 126: 13.74
+	Hs
		1027123 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN283_HUMAN (237-339): 9.16e-20: 97.9: 17.42
+	Hs
		549158 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN250_HUMAN (262-453): 5.39e-10: 66.3: 21.89