HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: ZN131 (P52739)
Zinc finger protein 131
Gene: ZNF131

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	22467880, 26841866
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 560 Hs			1 623
+	Hs
		316135 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN184_HUMAN (118-623): 1.31e-177: 523: 14.13
+	Hs
		315988 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN131_HUMAN (1-623): 3.77e-171: 502: 100.00
+	Hs
		123331 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		ZKSC7_HUMAN (352-622): 1.14e-54: 200: 15.83
+	Hs
		64140 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN729_HUMAN (78-621): 5.27e-151: 469: 13.57
+	Hs
		67424 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN850_HUMAN (2-479): 3.83e-131: 413: 14.55
+	Hs
		196551 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZBT24_HUMAN (16-609): 4.68e-112: 352: 20.55
+	Hs
		123275 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		ZN546_HUMAN (2-57): 4.74e-12: 71.1: 8.62
+	Hs
		316017 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZNF92_HUMAN (323-623): 5.78e-97: 310: 14.29
+	Hs
		1294636 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		ZN845_HUMAN (2-288): 1.51e-62: 225: 6.11
+	Hs
		1059199 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		ZKSC7_HUMAN (352-622): 1.14e-54: 200: 15.83
+	Hs
		316188 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZKSC7_HUMAN (352-622): 1.14e-54: 200: 15.83
+	Hs
		316190 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN624_HUMAN (1-258): 5.06e-50: 188: 4.98
+	Hs
		316196 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN107_HUMAN (2-264): 4.62e-45: 173: 5.96
+	Hs
		316199 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN214_HUMAN (310-463): 2.47e-36: 146: 19.91
+	Hs
		316039 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZKSC8_HUMAN (383-510): 2.34e-21: 100: 18.24
+	Hs
		315965 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZNF7_HUMAN (6-285): 4.49e-16: 84: 9.22
+	Hs
		316192 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN629_HUMAN (444-623): 9.99e-13: 73.2: 6.11
+	Hs
		316072 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN771_HUMAN (261-369): 1.19e-11: 68.2: 30.91
+	Hs
		563302 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZNF16_HUMAN (1-140): 8.38e-22: 101: 4.93
+	Hs
		549158 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN250_HUMAN (2-112): 6.78e-18: 89.2: 8.85