HitPredict

Interactor 1: ASCC3 (Q8N3C0)
Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)
Gene: ASCC3

Interactor 2: ASCC1 (Q8N9N2)
Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50)
Gene: ASCC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.726

The method score is based on:

Property Details
Experiments 29997253, 32099016, 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006307 - DNA alkylation repair
GO:0016607 - nuclear speck
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2202
Hs

1 400
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024