HitPredict

Interactor 1: ASCC3 (Q8N3C0)
Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)
Gene: ASCC3

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2202 Hs			1 523
+	Hs
		516589 ASCC3_HUMAN (1-2202): 0: 1789: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1232194 ASCC3_HUMAN (1-2202): 0: 1789: 100.00		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		1232198 ASCC3_HUMAN (1-2202): 0: 1789: 100.00		RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04
+	Sp
		678721 BRR2_SCHPO (16-2182): 0: 1346: 33.09		PABP_SCHPO (2-149): 1.81e-23: 106: 15.39
+	Sc
		376698 BRR2_YEAST (21-2180): 0: 1191: 30.42		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		1204680 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1263493 DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		571527 DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		134137 DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1074486 SKI2_HUMAN (445-899): 1.93e-85: 310: 21.98		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1069733 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613512 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		613538 DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		133858 DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Sc
		376837 MTR4_YEAST (1285-1848): 1.48e-90: 322: 21.35		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		134018 DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		1077436 DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		571469 DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1271643 DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		571581 DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14