HitPredict

Interactor 1: PALS1 (Q8N3R9)
Protein PALS1 (MAGUK p55 subfamily member 5) (Membrane protein, palmitoylated 5) (Protein associated with Lin-7 1)
Gene: PALS1

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 33961781, 27521426, 24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 675 Hs			1 779
+	Hs
		1118988 PALS1_HUMAN (1-675): 0: 561: 100.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Mm
		1225209 PALS1_MOUSE (1-675): 0: 559: 96.74		AMOL2_MOUSE (1-779): 2.27e-58: 214: 86.17
+	Hs
		1222245 PALS1_HUMAN (1-675): 0: 561: 100.00		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Mm
		1257596 PALS1_MOUSE (1-675): 0: 559: 96.74		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Mm
		1322042 PALS1_MOUSE (1-675): 0: 559: 96.74		AMOL1_MOUSE (1-761): 1.46e-38: 156: 38.96
+	Hs
		1021508 DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1118954 MPP7_HUMAN (122-674): 6.17e-127: 389: 36.06		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		958864 EM55_HUMAN (190-674): 1.63e-125: 382: 29.36		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Mm
		1257595 PALS2_MOUSE (134-674): 7.21e-143: 429: 34.05		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Hs
		958865 EM55_HUMAN (190-674): 1.63e-125: 382: 29.36		MYH4_HUMAN (27-765): 3.23e-24: 111: 10.70
+	Hs
		728468 EM55_HUMAN (190-674): 1.63e-125: 382: 29.36		MYH11_HUMAN (207-773): 7.92e-24: 110: 11.36
+	Mm
		936586 DLG4_MOUSE (7-671): 3.43e-130: 402: 20.84		ROCK2_MOUSE (307-661): 3.25e-12: 72.4: 17.02