HitPredict

Interactor 1: SYNPO (Q8N3V7)
Synaptopodin
Gene: SYNPO

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0015629 - actin cytoskeleton
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 929 Hs			1 817
+	Hs
		1232640 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Mm
		1113203 Q3URF1_MOUSE (245-929): 1.85e-72: 254: 79.69		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		88462 D3Z656_MOUSE (364-822): 4.74e-12: 72.4: 12.83		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		1164093 PCLO_MOUSE (8-877): 4.75e-11: 69.3: 9.17		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		1232615 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48
+	Mm
		581225 NFH_MOUSE (300-712): 1.27e-09: 64.2: 14.69		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		1200041 PCLO_HUMAN (256-925): 7.7e-18: 91.6: 10.83		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		297818 K0754_HUMAN (615-926): 1.87e-16: 87: 12.66		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Mm
		88458 D3Z656_MOUSE (364-822): 4.74e-12: 72.4: 12.83		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Mm
		1143433 SYNJ1_MOUSE (374-920): 1.64e-11: 70.8: 9.55		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Mm
		581224 NFH_MOUSE (300-712): 1.27e-09: 64.2: 14.69		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		1050035 CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15