HitPredict

Interactor 1: SYNPO (Q8N3V7)
Synaptopodin
Gene: SYNPO

Interactor 2: COR1B (Q9BR76)
Coronin-1B (Coronin-2)
Gene: CORO1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 929 Hs			1 489
+	Hs
		1232642 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		COR1C_HUMAN (4-484): 1.14e-119: 360: 72.77
+	Hs
		1232608 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		COR2A_HUMAN (1-487): 6.49e-96: 301: 44.13
+	Mm
		292596 Q3URF1_MOUSE (245-929): 1.85e-72: 254: 79.69		COR1A_MOUSE (4-481): 3.96e-108: 330: 63.05
+	Hs
		1232603 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		POC1A_HUMAN (256-436): 2.61e-19: 91.9: 9.24
+	Hs
		1300995 CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24		COR1C_HUMAN (4-484): 1.14e-119: 360: 72.77
+	Hs
		64078 L37A2_HUMAN (155-920): 8.41e-13: 75: 11.66		COR1A_HUMAN (4-481): 3.61e-109: 333: 63.47
+	Hs
		678286 CRBG2_HUMAN (297-906): 3.35e-09: 63.1: 13.93		COR1A_HUMAN (4-481): 3.61e-109: 333: 63.47
+	Dm
		973546 CPN_DROME (512-927): 2.92e-09: 63.1: 10.69		Q9W3W1_DROME (10-458): 4.65e-72: 249: 28.63
+	Dm
		90207 CPN_DROME (512-927): 2.92e-09: 63.1: 10.69		D6W4T8_DROME (10-458): 3.1e-71: 247: 28.63
+	Hs
		903152 IF4G1_HUMAN (317-895): 9.56e-36: 149: 13.46		WDR5_HUMAN (4-111): 3.06e-15: 78.8: 15.46
+	Hs
		1056932 MDC1_HUMAN (24-925): 1.38e-27: 123: 12.28		SNR40_HUMAN (252-488): 2.91e-20: 93.9: 9.13
+	Hs
		152663 KMT2D_HUMAN (66-925): 5.14e-09: 62.8: 9.93		WDR5B_HUMAN (4-203): 7.81e-40: 148: 19.51
+	Hs
		903374 KMT2C_HUMAN (145-901): 1.99e-13: 77.3: 11.38		WDR5_HUMAN (4-111): 3.06e-15: 78.8: 15.46
+	Hs
		1083355 CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24		RBBP7_HUMAN (31-163): 1.15e-16: 84: 21.43
+	Hs
		997865 CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24		RBBP4_HUMAN (31-163): 1.65e-15: 80.5: 20.00
+	Hs
		903450 CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24		WDR5_HUMAN (4-111): 3.06e-15: 78.8: 15.46
+	Hs
		997936 CHD7_HUMAN (237-601): 5.85e-09: 62.4: 9.28		RBBP4_HUMAN (31-163): 1.65e-15: 80.5: 20.00
+	Mm
		903669 KMT2C_MOUSE (298-888): 2.48e-09: 63.8: 15.41		WDR5_MOUSE (4-111): 3.06e-15: 78.8: 15.46
+	Hs
		152622 KMT2D_HUMAN (66-925): 5.14e-09: 62.8: 9.93		WDR5_HUMAN (4-111): 3.06e-15: 78.8: 15.46