HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	37014752, 33849069, 20601937
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016604 - nuclear body
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 560 Hs			1 1102
+	Hs
		1059179 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		316118 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		327857 CBX7_HUMAN (1-250): 1.04e-38: 144: 30.71		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273894 CBX8_HUMAN (1-259): 7.16e-33: 131: 28.22		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		203754 SUV91_HUMAN (4-154): 1.01e-32: 131: 21.15		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		949818 CBX1_HUMAN (17-163): 1.89e-39: 144: 21.05		U17L2_HUMAN (158-684): 1.09e-103: 338: 19.05
+	Hs
		203721 SUV91_HUMAN (4-154): 1.01e-32: 131: 21.15		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		203753 SUV91_HUMAN (4-154): 1.01e-32: 131: 21.15		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		203811 SUV91_HUMAN (4-154): 1.01e-32: 131: 21.15		UBP24_HUMAN (200-587): 2.93e-95: 337: 24.41