HitPredict

Interactor 1: NIN (Q8N4C6)
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
Gene: NIN

Interactor 2: CP250 (Q9BV73)
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)
Gene: CEP250

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28718761, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0008104 - protein localization GO:0010457 - centriole-centriole cohesion
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 2442
+	Hs
		969605 NIN_HUMAN (1-2090): 0: 617: 100.00		CENPE_HUMAN (1-1454): 3.09e-50: 200: 9.53
+	Hs
		1233482 NIN_HUMAN (1-2090): 0: 617: 100.00		MYH13_HUMAN (27-621): 4.59e-10: 67.8: 13.95
+	Hs
		149049 NIN_HUMAN (1-2090): 0: 617: 100.00		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		1034574 GOGA4_HUMAN (2-1081): 4.23e-31: 136: 12.36		GOGA4_HUMAN (3-1824): 1.71e-65: 250: 11.17
+	Hs
		725095 MYH10_HUMAN (12-1201): 4.09e-38: 159: 12.98		MYH10_HUMAN (1424-2376): 3.63e-37: 157: 13.43
+	Hs
		725097 MYH10_HUMAN (12-1201): 4.09e-38: 159: 12.98		MYH11_HUMAN (1406-2417): 3.68e-37: 157: 14.71
+	Hs
		828575 CENPF_HUMAN (29-810): 8.47e-25: 116: 11.38		CENPE_HUMAN (1-1454): 3.09e-50: 200: 9.53
+	Hs
		969580 CENPE_HUMAN (1236-2090): 8.51e-24: 112: 11.72		CENPE_HUMAN (1-1454): 3.09e-50: 200: 9.53
+	Hs
		528435 MYH8_HUMAN (111-1154): 9.6e-31: 135: 11.88		MYH4_HUMAN (1-882): 5.16e-36: 153: 14.25
+	Hs
		1034577 GOGA4_HUMAN (2-1081): 4.23e-31: 136: 12.36		GOGB1_HUMAN (1634-2442): 3.53e-19: 97.7: 11.58
+	Hs
		148461 MYH10_HUMAN (12-1201): 4.09e-38: 159: 12.98		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		828567 CENPF_HUMAN (29-810): 8.47e-25: 116: 11.38		CENPF_HUMAN (1746-2440): 6.7e-19: 96.9: 11.02
+	Hs
		528432 MYH8_HUMAN (111-1154): 9.6e-31: 135: 11.88		MYH13_HUMAN (27-621): 4.59e-10: 67.8: 13.95
+	Hs
		148769 GOGA4_HUMAN (2-1081): 4.23e-31: 136: 12.36		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		148338 TPR_HUMAN (30-1095): 7.67e-28: 126: 10.73		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		148466 MYH11_HUMAN (1-942): 4.75e-27: 123: 10.69		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		148534 CENPF_HUMAN (29-810): 8.47e-25: 116: 11.38		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		148460 MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55