HitPredict

Interactor 1: Q8N4I8 (Q8N4I8)
KLHL3 protein
Gene: KLHL3

Interactor 2: Q8N4I8 (Q8N4I8)
KLHL3 protein
Gene: KLHL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	25416956
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0050801 - monoatomic ion homeostasis GO:0070294 - renal sodium ion absorption GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 301 Hs			1 301
+	Hs
		1355221 KLHL3_HUMAN (1-301): 3.39e-120: 358: 100.00		KLHL3_HUMAN (1-301): 3.39e-120: 358: 100.00
+	Hs
		307227 KLHL3_HUMAN (1-301): 3.39e-120: 358: 100.00		KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00
+	Hs
		1377320 KLH20_HUMAN (7-297): 3.32e-114: 343: 45.02		KLH20_HUMAN (7-297): 3.32e-114: 343: 45.02
+	Hs
		1164602 KLHL3_HUMAN (1-301): 3.39e-120: 358: 100.00		KLH17_HUMAN (29-298): 9.54e-106: 323: 51.48
+	Hs
		307154 KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00		KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00
+	Hs
		1120826 KLHL3_HUMAN (1-301): 3.39e-120: 358: 100.00		KLH12_HUMAN (30-295): 8.92e-103: 313: 45.87
+	Hs
		307188 KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00		KLH17_HUMAN (29-298): 9.54e-106: 323: 51.48
+	Hs
		1120830 KLH20_HUMAN (7-297): 3.32e-114: 343: 45.02		KLH12_HUMAN (30-295): 8.92e-103: 313: 45.87
+	Hs
		307182 KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00		KLH12_HUMAN (30-295): 8.92e-103: 313: 45.87
+	Hs
		1164636 KLH20_HUMAN (7-297): 3.32e-114: 343: 45.02		KLH24_HUMAN (30-298): 3.52e-98: 302: 40.15
+	Hs
		1121506 KLHL3_HUMAN (1-301): 3.39e-120: 358: 100.00		KLH26_HUMAN (11-297): 1.33e-91: 285: 30.31
+	Hs
		1049352 KLHL3_HUMAN (1-301): 3.39e-120: 358: 100.00		KEAP1_HUMAN (3-286): 3.33e-89: 279: 32.41
+	Hs
		307225 KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00		KLH13_HUMAN (5-297): 1.19e-95: 297: 30.51
+	Hs
		1377325 KLH20_HUMAN (7-297): 3.32e-114: 343: 45.02		IPP_HUMAN (14-295): 7.93e-93: 287: 32.75
+	Hs
		1121511 KLH20_HUMAN (7-297): 3.32e-114: 343: 45.02		KLH26_HUMAN (11-297): 1.33e-91: 285: 30.31
+	Hs
		307183 KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00		KLH26_HUMAN (11-297): 1.33e-91: 285: 30.31
+	Hs
		1356007 KLH20_HUMAN (7-297): 3.32e-114: 343: 45.02		KLH21_HUMAN (19-299): 1.06e-89: 280: 32.62
+	Hs
		307172 KLHL2_HUMAN (3-301): 3.69e-113: 340: 70.00		KEAP1_HUMAN (3-286): 3.33e-89: 279: 32.41
+	Hs
		1049265 Q8N4I8_HUMAN (1-301): 1.27e-111: 326: 100.00		KEAP1_HUMAN (3-286): 3.33e-89: 279: 32.41