HitPredict

Interactor 1: DCLK2 (Q8N568)
Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)
Gene: DCLK2

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0021766 - hippocampus development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Hs			1 817
+	Hs
		1234199 DCLK2_HUMAN (1-766): 0: 782: 100.00		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Hs
		166604 DCLK1_HUMAN (1-744): 0: 675: 65.34		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Mm
		1164085 DCLK1_MOUSE (1-744): 0: 671: 62.57		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		166629 DCLK1_HUMAN (1-744): 0: 675: 65.34		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Hs
		166544 DCLK1_HUMAN (1-744): 0: 675: 65.34		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Hs
		208290 DCX_HUMAN (6-354): 9.62e-138: 412: 66.94		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Rn
		192509 KCC2B_RAT (388-760): 2.46e-136: 415: 33.76		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Mm
		292337 DCX_MOUSE (6-351): 1.51e-138: 414: 67.22		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Rn
		192513 KCC2D_RAT (388-749): 4.46e-134: 409: 34.06		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Hs
		166601 DCLK1_HUMAN (1-744): 0: 675: 65.34		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48
+	Hs
		1038896 KCC2B_HUMAN (388-757): 1.89e-131: 407: 33.50		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		1038993 KCC2G_HUMAN (388-753): 7.49e-133: 407: 34.87		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		1039101 KCC2D_HUMAN (388-698): 3.75e-133: 405: 37.46		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		1252529 PAK5_HUMAN (9-658): 4.64e-139: 428: 21.48		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Mm
		250629 KCC2D_MOUSE (388-698): 3.75e-133: 405: 37.46		LNX1_MOUSE (273-773): 1.71e-32: 137: 12.03
+	Mm
		292336 DCX_MOUSE (6-351): 1.51e-138: 414: 67.22		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Mm
		1143346 KCC2D_MOUSE (388-698): 3.75e-133: 405: 37.46		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		1021556 M3K3_HUMAN (17-650): 4.69e-140: 427: 16.67		DLG1_HUMAN (435-691): 6e-19: 94.1: 15.04
+	Hs
		1050040 M3K3_HUMAN (17-650): 4.69e-140: 427: 16.67		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15
+	Hs
		1026159 PAK1_HUMAN (149-652): 1.76e-137: 418: 21.81		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15