Interactor 1: PGRC1 (O00264)
Membrane-associated progesterone receptor component 1 (mPR) (Dap1) (IZA)
Gene: PGRMC1

Interactor 2: PGRC2 (O15173)
Membrane-associated progesterone receptor component 2 (Progesterone membrane-binding protein) (Steroid receptor protein DG6)
Gene: PGRMC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 32296183, 35271311, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyt-b5~Cyt-b5
Common GO terms GO:0005496 - steroid binding
GO:0005576 - extracellular region
GO:0005783 - endoplasmic reticulum
GO:0012505 - endomembrane system
GO:0016020 - membrane
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 195
Hs

1 223
+ Hs
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024