HitPredict

Interactor 1: TAB3 (Q8N5C8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 712 Hs			1 400
+	Hs
		808768 TAB3_HUMAN (1-712): 8.19e-99: 321: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		847075 SMCA4_HUMAN (153-599): 1.86e-39: 159: 11.43		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		125579 TAB3_HUMAN (1-712): 8.19e-99: 321: 100.00		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		203253 SYNJ1_HUMAN (252-685): 6.15e-21: 100: 11.19		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		808409 SMCA4_HUMAN (153-599): 1.86e-39: 159: 11.43		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808408 SMCA2_HUMAN (176-599): 1.02e-36: 150: 13.59		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808853 CHAP1_HUMAN (63-511): 1.2e-19: 96: 13.16		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		125260 SMCA4_HUMAN (153-599): 1.86e-39: 159: 11.43		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		125259 SMCA2_HUMAN (176-599): 1.02e-36: 150: 13.59		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		554367 MUC1_HUMAN (54-680): 4.91e-23: 107: 9.24		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		125274 SC24C_HUMAN (210-493): 5.8e-12: 71.3: 13.44		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		123777 SPT5H_HUMAN (58-209): 8.32e-09: 61.3: 13.64		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		846873 SMCA2_HUMAN (176-599): 1.02e-36: 150: 13.59		SMUF2_HUMAN (156-326): 4.16e-25: 109: 11.92
+	Hs
		847097 SMCA4_HUMAN (153-599): 1.86e-39: 159: 11.43		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1264807 TITIN_HUMAN (134-417): 2.57e-09: 63.2: 9.72		SMUF2_HUMAN (156-326): 4.16e-25: 109: 11.92
+	Hs
		867138 SC24C_HUMAN (210-493): 5.8e-12: 71.3: 13.44		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09